Am Pharma

Neratinib use to treatment of various type of hormone receptor-positive breast cancer (breast cancer that depends on hormones such as estrogen to grow) in adults after treatment with trastuzumab (Herceptin) and other medications. Neratinib use along with capecitabine (Xeloda) to treatment various type of advanced hormone receptor-positive breast cancer or breast cancer that has spread to other parts of the body after treatment with at least two other medications. Neratinib like a class of medications call kinase inhibitors. It  blocks the action of an abnormal protein that signals cancer cells to multiply.

Retatrutide 15 mg is an investigational drug that is a novel triple agonist of the glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon receptors. ¹ Clinical trials have shown that retatrutide, at various doses including those approaching 15 mg, has resulted in significant weight loss in individuals with obesity and type 2 diabetes

Retatrutide (LY3437943) is an agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and glucagon receptors. Its dose-response relationships with respect to side effects, safety, and efficacy for the treatment of obesity are not known.

This medicine is another form of the drug vardenafil. These other forms are called generic forms. Vilitra 20mg is used to treat impotence or erectile dysfunction in men.

10 mg/mL Propofol Injection Uses:

Propofol is a short-acting intravenous anesthetic agent primarily used for:

1. Induction and Maintenance of General Anesthesia

• Propofol is commonly used to induce unconsciousness before surgery or other medical procedures.
• It can also be used to maintain anesthesia throughout the procedure.

2. Sedation for Mechanically Ventilated Patients in the ICU

• Propofol is used for sedation in critically ill patients who require mechanical ventilation.
• It helps keep the patient calm and comfortable while on the ventilator.

3. Procedural Sedation

• Propofol is frequently used for conscious sedation during minor procedures such as:
  • Endoscopy
  • Colonoscopy
  • Cardioversion

Benefits:

• Rapid onset: Induces sedation or anesthesia within 30-60 seconds.
• Short duration: Wears off quickly, allowing faster recovery.
• Smooth sedation: Provides good control over sedation depth.

Important Considerations:

• Propofol should only be administered by healthcare professionals trained in airway management and resuscitation.
• It can cause hypotension (low blood pressure) and respiratory depression.
• Requires close monitoring of vital signs during use.

Fluvoxamine is used to treat obsessive compulsive disorder (OCD). It belongs to a group of medicines known as selective serotonin reuptake inhibitors (SSRIs). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain. 


Voxa 100 Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is prescribed to treat depression, where it helps to make you feel better. This medicine is also used to treat people with obsessive-compulsive disorder.

600mg Glutathione Injection is a form of glutathione, which is a powerful antioxidant naturally present in the body. Glutathione plays a key role in protecting cells from oxidative stress and free radicals, detoxifying the body, and supporting the immune system. As an injectable form, it is often used for therapeutic purposes, especially in individuals with specific health conditions or to enhance certain bodily functions.

The primary uses of 600mg Glutathione Injection include:

1. Antioxidant Therapy: Glutathione is a potent antioxidant that helps neutralize harmful free radicals in the body. This can help protect cells from oxidative damage, which is associated with aging, chronic diseases, and some types of cancer.

2. Detoxification: Glutathione plays a significant role in detoxifying the liver and supporting the body's natural detoxification processes. It helps break down and remove harmful substances like heavy metals, environmental toxins, and metabolic waste products.

3. Skin Whitening and Brightening: Glutathione injections are often used in some regions for skin lightening or whitening. The idea is that glutathione inhibits the production of melanin, the pigment responsible for skin color. It may reduce skin pigmentation issues such as hyperpigmentation, dark spots, or melasma.

4. Liver Health: Glutathione is vital for liver function, especially in individuals with liver disease or liver damage due to alcohol, toxins, or hepatitis. It can help support the liver's detoxifying capabilities and reduce oxidative stress, which may improve liver function in patients with conditions such as non-alcoholic fatty liver disease (NAFLD) or hepatitis.

5. Improved Immune Function: Glutathione is involved in the proper functioning of the immune system. It helps to enhance the body's ability to fight off infections, particularly by promoting the activity of T-cells and other immune cells.

6. Neurological Health: Due to its antioxidant properties, glutathione is sometimes used to support brain health and protect against conditions like Parkinson's disease, Alzheimer's disease, and multiple sclerosis, where oxidative stress plays a role in disease progression.

600 mg Glutathione Injection Uses:

Glutathione is a powerful antioxidant naturally present in the body. It helps neutralize free radicals, detoxifies harmful substances, and supports various metabolic processes. Glutathione injections are used for a range of therapeutic and cosmetic purposes, particularly in enhancing detoxification and promoting skin health.

Uses of 600 mg Glutathione Injection:

1. Skin Whitening and Brightening:

   • Glutathione injections are commonly used for skin lightening or whitening. It works by inhibiting the production of melanin, the pigment responsible for dark skin. Many people use glutathione to lighten their skin tone or reduce hyperpigmentation, such as dark spots, melasma, and age spots.

2. Detoxification:

   • Glutathione is a major antioxidant in the liver, and glutathione injections are sometimes used to support liver detoxification. The injection helps to neutralize toxins, reduce oxidative stress, and improve liver function. It is sometimes used as part of detox programs to remove heavy metals and environmental toxins from the body.

3. Anti-Aging:

   • As a potent antioxidant, glutathione helps combat oxidative damage caused by free radicals, slowing down the signs of aging. Glutathione injections are sometimes used to reduce wrinkles, fine lines, and skin dullness, improving overall skin appearance.

4. Immune System Support:

   • Glutathione boosts the immune system by enhancing the production of white blood cells, thereby improving the body’s ability to fight infections. It may also be used in the management of conditions such as chronic fatigue or to support general immune health.

5. Management of Skin Conditions:

   • It is sometimes used as an adjunct treatment for various skin conditions like psoriasis, eczema, and acne, as glutathione’s antioxidant properties can help reduce inflammation and oxidative stress that contribute to these conditions.

20mg/2ml Sodium Hypochlorite E.P. Injection is a medical solution used primarily as a disinfectant and antiseptic. It is commonly used in medical settings for various purposes, including wound irrigation and dental treatments. Sodium hypochlorite is a strong oxidizing agent that is effective in killing bacteria, viruses, and fungi.

Main Uses of 20mg/2ml Sodium Hypochlorite E.P. Injection:

1. Wound Irrigation and Cleansing:

   • Sodium Hypochlorite is often used for wound irrigation, particularly for chronic or infected wounds, to help cleanse and disinfect the area, reducing the risk of infection.
   • It is effective at removing debris and bacteria from wounds while promoting the healing process.

2. Dental Procedures:

   • Sodium Hypochlorite is frequently used in root canal therapy to irrigate the root canals, helping to sterilize the area and remove organic tissue and bacteria from within the canal.
   • It can also be used in dental disinfection procedures to help prevent infections in the gums or mouth.

3. Surgical Use:

   • In certain surgical settings, sodium hypochlorite solution may be used for cleaning surgical sites or for disinfection of medical instruments and equipment, ensuring that any microbial contamination is eliminated.

4. Antiseptic for Skin Infections:

   • It may also be used in certain formulations as a topical antiseptic for minor skin infections or cuts, to reduce the risk of infection and promote faster healing.

How It Works:

• Sodium Hypochlorite works by oxidizing and breaking down the cell walls of bacteria, viruses, and fungi. This destroys the microorganisms, preventing infection or contamination.
• In wound care, it helps to cleanse the wound bed by removing dead tissue and reducing the microbial load, which is essential for wound healing.
• In dental treatments, it effectively cleans and sterilizes the root canal space, removing any remaining bacteria or debris that may cause future infection.

Infimab is a brand name for an infliximab injection, which is a biologic drug that is commonly used for treating various autoimmune diseases. The 100 mg Infimab (Infliximab) injection is used for the following conditions:

1. Rheumatoid Arthritis (RA):

   • Infliximab is used to treat rheumatoid arthritis, an autoimmune disease where the immune system attacks the joints, causing inflammation, pain, and potential joint damage. It is often used in combination with methotrexate to help reduce symptoms, prevent joint damage, and improve function.

2. Inflammatory Bowel Diseases (IBD):

   • Crohn's Disease: Infliximab is used to treat Crohn's disease, a chronic inflammatory bowel disease (IBD) that affects the digestive tract, causing symptoms such as abdominal pain, diarrhea, and weight loss.
   • Ulcerative Colitis: It is also used for treating ulcerative colitis, another type of IBD that primarily affects the colon and rectum, causing symptoms like bloody diarrhea, abdominal cramps, and urgency.

3. Ankylosing Spondylitis:

   • Infliximab is used in the treatment of ankylosing spondylitis, a type of arthritis that affects the spine and large joints, causing stiffness and pain. It helps reduce inflammation and improve mobility in affected areas.

4. Psoriatic Arthritis:

   • Infliximab is also used to treat psoriatic arthritis, a form of arthritis associated with the skin condition psoriasis. It helps reduce joint inflammation and skin lesions.

5. Plaque Psoriasis:

   • Infliximab is used for plaque psoriasis, a chronic autoimmune skin condition characterized by red, scaly patches. It helps reduce the severity of skin lesions.

6. Other Autoimmune Diseases:

   • Infliximab may also be used off-label for other autoimmune conditions, such as juvenile idiopathic arthritis (JIA) or systemic lupus erythematosus (SLE), depending on a healthcare provider’s recommendation.

Mechanism of Action:

Infliximab is a monoclonal antibody that works by targeting and inhibiting tumor necrosis factor-alpha (TNF-alpha), a protein involved in the inflammatory response in the body. By blocking TNF-alpha, Infliximab reduces inflammation and helps control the immune system’s abnormal response, which is responsible for many of the symptoms of autoimmune diseases.

Administration:

• Infliximab (Infimab) is typically administered via intravenous (IV) infusion in a healthcare setting.
• The 100 mg dose is typically part of a larger infusion regimen, with doses adjusted based on the specific condition being treated. The exact dosing schedule varies depending on the condition and the patient’s response to treatment.
• The initial dose may be followed by additional infusions at specified intervals, such as every 6 to 8 weeks for maintenance therapy.

Common Side Effects:

• Infusion reactions (such as fever, chills, or rash during the infusion)
• Upper respiratory infections (e.g., sinusitis, sore throat)
• Headache
• Abdominal pain
• Nausea

Glutathione Injection (1200 mg) Uses:

Glutathione injection contains glutathione, a powerful antioxidant naturally found in cells. It helps neutralize free radicals, detoxifies the body, and supports various biological functions. Glutathione injections are commonly used for medical and cosmetic purposes.

Medical Uses:

1. Liver Disease Support:

   • Used to manage chronic liver diseases such as fatty liver, hepatitis, and cirrhosis by reducing oxidative stress and improving liver function.

2. Parkinson’s Disease:

   • Glutathione may help improve symptoms by reducing oxidative damage in the brain and supporting nerve function.

3. Cancer Therapy Support:

   • Administered to reduce the side effects of chemotherapy and radiotherapy by protecting normal cells from oxidative damage.

4. Autoimmune Diseases:

   • May be used as an adjunct therapy for autoimmune disorders to reduce inflammation and boost the immune system.

Sodium Hyaluronate 20 mg/2 mL Injection is a medication commonly used in orthopedic and dermatologic treatments, due to its properties as a viscosupplement and lubricant. Sodium hyaluronate is a form of hyaluronic acid, a naturally occurring substance in the body that is a major component of joint fluids, skin, and connective tissues.

Primary Uses of Sodium Hyaluronate 20 mg/2 mL Injection:

1. Osteoarthritis (OA) of the Knee

   • The most common use of sodium hyaluronate injection is for viscosupplementation in the treatment of osteoarthritis (OA), especially in the knee joint. In OA, the natural hyaluronic acid in the joint fluid is depleted, leading to increased friction and pain in the joints. The injection provides a synthetic replacement for hyaluronic acid, helping to lubricate the joint and reduce pain, inflammation, and stiffness, and improving mobility.
   • It is often used in patients who do not respond adequately to oral medications or other forms of treatment like physical therapy or corticosteroid injections.

2. Joint Injections for Other Joints

   • While most commonly used in the knee, sodium hyaluronate may also be used for viscosupplementation in other joints affected by osteoarthritis, such as the hip, shoulder, and ankle.

3. Post-Surgical Treatment

   • Sodium hyaluronate may also be used in the post-surgical treatment of joints to help improve recovery by providing lubrication and promoting healing. It can reduce swelling and pain, which are common after joint surgeries, particularly in the knee.

4. Dermatological Uses (in certain cases)

   • Although less common, sodium hyaluronate injections can be used in dermatology for aesthetic purposes, such as in dermal fillers to add volume to the skin or reduce wrinkles. These uses typically involve higher concentrations of sodium hyaluronate and are more common in cosmetic procedures.

How Sodium Hyaluronate Works:

Sodium hyaluronate mimics the natural hyaluronic acid found in the synovial fluid of joints, which acts as a lubricant and shock absorber. By injecting sodium hyaluronate into the joint, it helps restore the normal viscosity and elasticity of the synovial fluid, improving joint function and reducing pain.

Common Side Effects:

• Pain or swelling at the injection site
• Bruising at the injection site
• Redness or warmth at the injection site
• Joint stiffness
• Temporary increase in joint pain (known as flare reaction)

Serious Side Effects (Rare):

• Infection at the injection site
• Severe allergic reactions (e.g., rash, difficulty breathing)
• Joint effusion (excess fluid in the joint)
• Skin reactions (e.g., rash or hives)

Precautions:

• Infection Risk: The injection should not be administered if there is an active infection or inflammation in the joint.
• Allergy: Inform your healthcare provider if you have any history of allergies to hyaluronic acid or other injectable materials.
• Pregnancy and Breastfeeding: The safety of sodium hyaluronate during pregnancy or breastfeeding has not been fully established, so it should only be used if prescribed by a healthcare professional after weighing the risks and benefits.

Alburel Human Normal Albumin 20g Injection is a form of human albumin, a protein derived from human blood plasma. Albumin plays a critical role in maintaining oncotic pressure (the pressure that helps keep fluid within blood vessels) and transporting substances like hormones, vitamins, and medications in the bloodstream.

Primary Uses of Alburel Human Normal Albumin 20g Injection:

1. Hypoalbuminemia

   • Alburel is commonly used to treat hypoalbuminemia, which is a condition characterized by low levels of albumin in the blood. Hypoalbuminemia can occur due to various causes, including liver disease, nephrotic syndrome, malnutrition, and acute or chronic illnesses.
   • The injection helps restore albumin levels, improving the body’s ability to maintain fluid balance, prevent edema (swelling), and support proper organ function.

2. Shock and Trauma

   • Alburel can be used in the management of shock, particularly hypovolemic shock (shock due to low blood volume) caused by trauma, burns, surgery, or severe dehydration.
   • It helps to increase blood volume, improve circulatory function, and stabilize the patient by drawing fluid into the bloodstream from the tissues.

3. Burns

   • In cases of severe burns, albumin is used to treat fluid loss, stabilize blood pressure, and prevent shock. Burn patients often experience significant loss of plasma proteins due to damaged skin and increased capillary permeability, and albumin helps to replace lost proteins and restore fluid balance.

4. Liver Disease (Cirrhosis and Ascites)

   • In patients with cirrhosis of the liver and ascites (fluid accumulation in the abdomen), albumin helps to manage the condition by improving the volume and composition of blood, thus reducing fluid retention and helping to prevent complications like hepatorenal syndrome (kidney failure due to liver disease).

5. Neonatal Hemolytic Disease

   • Alburel may be used in the treatment of neonatal hemolytic disease, particularly in newborns with severe jaundice and anemia. In such cases, albumin helps to prevent bilirubin toxicity by binding to excess bilirubin, which is a byproduct of red blood cell breakdown.

6. Chronic Kidney Disease and Nephrotic Syndrome

   • In nephrotic syndrome or chronic kidney disease, where there is excessive loss of protein in the urine, albumin is used to maintain plasma protein levels and help manage edema (swelling), especially when kidney function is severely compromised.

How Alburel Human Normal Albumin Works:

Albumin is a natural protein that maintains the osmotic pressure of blood, preventing the leakage of fluid from blood vessels into the tissues. It also serves as a carrier for various substances, such as hormones, fatty acids, and drugs, and helps transport bilirubin in the blood. By restoring low albumin levels in the blood, Alburel helps maintain fluid balance, improve circulation, and prevent or treat complications associated with fluid imbalances, such as edema and shock

Alburel 20gm Solution for Infusion is used to treat blood volume loss. It works by replacing the body fluids lost due to excessive trauma, bleeding, surgery, or kidney dialysis. Thus, it is helpful in treating low blood albumin levels.

Alburel 20gm Solution for Infusion must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergies to this injection. Before taking it, inform the doctor you are suffering from any severe heart disease.

Oxybutynin (Generic Ditropan) Tablets for the treatment of overactive bladder.
It relieves urinary symptoms like frequent urination, urgent need to urinate and inability to control urination.

Phenergan 25 Tablet used in the treatment of nausea and vomiting related to certain conditions like before/after surgery or motion sickness. It may also be used to treat allergic conditions such as rash, itching, and runny nose.

In Treatment of NauseaPhenergan 25 Tablet blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or any other medical treatment. This medicine helps you recover more comfortably.

Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes
In a recent study, FOXO4-DRI decreased levels of p53, p21, and p16 in the testes of aged mice, when compared to young mice (Zhang et al., 2020). Therefore, our study and published work collectively showed that FOXO4-DRI was able to remove senescent cells created by different methods.
FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice

Gammaren Injection (5%) is an intravenous immunoglobulin (IgG) preparation derived from human plasma. It contains a high concentration of immunoglobulins, which are antibodies that help the immune system fight infections. Gammaren Injection is primarily used to treat immune deficiency disorders and conditions where the immune system is compromised or malfunctioning.

Main Uses of Gammaren Injection (5%):

1. Primary Immunodeficiency Disorders:

   • Gammaren is used to treat primary immunodeficiency diseases (PIDs), such as Common Variable Immunodeficiency (CVID) or X-linked agammaglobulinemia, in which the immune system fails to produce adequate antibodies. The injection helps boost immunity by providing the body with a concentrated dose of immunoglobulins to fight infections.

2. Secondary Immunodeficiency Disorders:

   • It is used in patients with secondary immunodeficiency, where the immune system is weakened due to other factors, such as chemotherapy, certain cancers (like leukemia or lymphoma), HIV/AIDS, or chronic infections. In these conditions, Gammaren provides the necessary antibodies to help fight infections.

3. Idiopathic Thrombocytopenic Purpura (ITP):

   • Gammaren is sometimes used in the treatment of idiopathic thrombocytopenic purpura (ITP), an autoimmune disorder where the immune system destroys platelets, leading to bleeding and bruising. The immunoglobulin helps increase platelet counts and reduce bleeding in ITP patients.

4. Autoimmune Diseases:

   • It is used to treat some autoimmune diseases, where the immune system mistakenly attacks the body’s tissues. Examples include Kawasaki disease (a condition in children that causes inflammation in blood vessels) and Guillain-Barré syndrome (a neurological disorder). Immunoglobulin therapy can help modulate the immune response and reduce inflammation in these conditions.

5. Post-Exposure Prophylaxis:

   • In some cases, Gammaren is used after exposure to certain viruses (like hepatitis B or measles) to prevent infection, particularly in individuals who are at high risk or who have an impaired immune response.

6. Bone Marrow Transplant (BMT):

   • Patients undergoing bone marrow transplants may receive Gammaren to provide passive immunity, as they are at high risk of infections due to a weakened immune system before the transplant fully takes effect.

How It Works:

• Gammaren Injection provides a source of immunoglobulins (IgG), which are antibodies that help fight infections by neutralizing pathogens (like bacteria, viruses, and fungi) and activating the immune system. The injection works by temporarily providing the body with a functional immune system, particularly in individuals whose immune system is compromised or deficient.
• The immunoglobulins in Gammaren work by binding to pathogens or infected cells and marking them for destruction by other immune cells, such as macrophages or T cells.

Albucel Injection (100 mL) is a human albumin solution used primarily in critical care settings to treat or prevent conditions related to low levels of albumin in the blood. Albumin is a protein produced by the liver and plays a critical role in maintaining blood volume, osmotic pressure, and fluid balance.

Main Uses of Albucel Injection (100 mL):

1. Hypovolemia and Shock:

   • Albucel Injection is used to restore blood volume in patients experiencing hypovolemia (low blood volume) due to conditions like severe burns, trauma, surgery, or hemorrhage. It helps maintain adequate circulation and tissue perfusion, preventing shock and ensuring that organs receive enough oxygen and nutrients.

2. Hypoalbuminemia:

   • Albucel is used to treat hypoalbuminemia, which is a condition characterized by low levels of albumin in the blood. This can occur due to liver disease (e.g., cirrhosis), nephrotic syndrome, kidney disease, or malnutrition. Albumin helps in maintaining oncotic pressure, and its infusion helps to pull fluid back into the bloodstream, preventing edema and helping in fluid balance.

3. Burns and Trauma:

   • In patients with severe burns or extensive trauma, Albucel may be used to restore plasma volume and prevent complications like fluid loss, shock, and edema. It can help improve blood pressure and organ function during the acute phase of injury.

4. Liver Disease (Cirrhosis or Liver Failure):

   • Albucel can be used to manage complications of liver cirrhosis or liver failure, such as ascites (fluid accumulation in the abdomen), as it helps in maintaining plasma volume and reducing the risk of fluid imbalances.

5. Nephrotic Syndrome:

   • In conditions like nephrotic syndrome, where the kidneys lose excessive amounts of protein (including albumin) into the urine, Albucel may be administered to replenish albumin levels in the blood and help restore normal blood volume and fluid balance.

6. Plasma Exchange (Therapeutic Apheresis):

   • Albucel can be used as part of a plasma exchange procedure in certain conditions, such as autoimmune diseases or severe kidney disease, to replace lost plasma proteins during the procedure.

How It Works:

• Albucel Injection contains human albumin, which helps to increase plasma oncotic pressure, promoting the movement of fluid back into the blood vessels from the tissues. This helps in restoring blood volume, reducing edema, and maintaining proper circulation. The albumin acts as a volume expander and is essential for maintaining proper fluid distribution throughout the body.

Administration:

• Albucel is usually administered intravenously by a healthcare professional. The exact dose and rate of infusion will depend on the specific condition being treated and the patient's overall health. It is important that the infusion is carefully monitored to avoid complications such as fluid overload.

Edaravone Injection (15 mg/ml) Uses:

Edaravone injection is primarily used for the treatment of neurological and neurodegenerative conditions due to its antioxidant properties. It works by reducing oxidative stress, which can cause damage to neurons.

Uses of Edaravone Injection:

1. Amyotrophic Lateral Sclerosis (ALS):

   • Edaravone is approved for the treatment of ALS, a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to muscle weakness, paralysis, and eventually respiratory failure.
   • It helps slow down the progression of physical disability by reducing oxidative damage to motor neurons.

2. Acute Ischemic Stroke (in some countries):

   • Edaravone may be used for treating acute ischemic stroke to reduce neurological damage by limiting the extent of brain cell injury caused by free radicals during ischemia (lack of blood supply) and reperfusion (restoration of blood flow).

How Edaravone Works:

• Antioxidant Action:
  • Edaravone scavenges free radicals and prevents oxidative stress-induced damage to cells, particularly neurons.
  • This helps reduce cell death and improves the survival of nerve cells, especially in conditions where oxidative stress plays a major role, such as ALS and stroke.

Common Side Effects:

• Headache
• Dizziness
• Fatigue
• Nausea
• Injection site reactions

Serious Side Effects:

• Allergic Reactions: Severe hypersensitivity or anaphylactic reactions may occur in rare cases.
• Liver or Kidney Impairment: Edaravone can affect liver and kidney function, requiring regular monitoring during treatment.
• Breathing difficulties: Edaravone may cause respiratory issues in some patients, particularly those with pre-existing lung conditions.

Precautions:

1. Kidney and Liver Function:
   • Regular monitoring of renal and hepatic function is recommended during treatment, especially in patients with pre-existing liver or kidney disorders.
2. Hypersensitivity Reactions:
   • Since Edaravone can cause severe allergic reactions, patients should be closely monitored during the initial phases of treatment.
3. Pregnancy and Breastfeeding:
   • It is not recommended for use during pregnancy or breastfeeding unless absolutely necessary, as its safety in these populations has not been fully established.

Hydroxypropyl Methylcellulose (HPMC) Injection is commonly used in the field of ophthalmology and other medical applications due to its ability to form a gel-like substance. This makes it useful as a viscosity-enhancing agent, lubricant, and stabilizer. Here are the primary uses of Hydroxypropyl Methylcellulose Injection:

Primary Uses of Hydroxypropyl Methylcellulose Injection:

1. Intraocular Surgery (Eye Surgeries):

   • HPMC injection is often used as a viscoelastic agent in various eye surgeries, such as cataract surgery, vitrectomy, and corneal transplant.
   • It is injected into the eye during these procedures to maintain intraocular pressure, protect the eye's delicate structures, and facilitate the surgical process by providing lubrication between surgical instruments and the eye tissue.
   • HPMC helps to preserve the shape of the eye's anterior chamber and reduces friction, preventing damage to sensitive tissues such as the corneal endothelium.

2. Lubricant in Ophthalmic Injections:

   • It is used in ophthalmic injections to lubricate and cushion the eye tissues during injection procedures.
   • The gel-like consistency created by HPMC helps to reduce the discomfort and trauma that may occur when administering drugs or performing injections into the eye.

3. Stabilizing Agent in Injectable Drug Formulations:

   • HPMC is used in some injectable drug formulations to stabilize the medication, improve its solubility, and enhance its physical properties.
   • By increasing the viscosity, HPMC helps to ensure that the drug stays in a stable form, reducing the risk of settling or separation during storage.

4. Wound Healing and Tissue Protection:

   • In some cases, HPMC injection is used in wound healing or tissue repair applications where its viscosity can help protect damaged tissues and provide a moist environment conducive to healing.
   • It is especially useful in applications requiring gentle lubrication or protection from external contaminants.

How Hydroxypropyl Methylcellulose Injection Works:

HPMC is a modified cellulose compound that has been chemically altered to increase its solubility and gelling properties. It forms a gel-like substance when injected into the body, which:

• Increases viscosity: This provides lubrication and stability, which is crucial in surgical and injection procedures.
• Protects delicate tissues: In ophthalmic surgeries, the gel helps to protect eye tissues from mechanical damage caused by surgical tools or instruments.
• Maintains fluid consistency: HPMC helps maintain the proper fluid dynamics during surgical interventions or drug delivery, ensuring that the medication remains in its optimal form.

Common Side Effects:

• Mild irritation or discomfort at the injection site (if administered locally)
• Blurred vision (temporary, particularly when used in ophthalmic surgery)
• Increased intraocular pressure (in rare cases, when used in eye surgeries)
• Allergic reactions (such as skin rash, itching, or swelling)
• Temporary eye discomfort or foreign body sensation (following eye surgeries)

Globucel Injection (100 mL) typically contains immunoglobulin (Ig), a substance derived from human plasma that contains antibodies. It is used to treat various immune deficiencies and autoimmune conditions.

Primary Uses of Globucel Injection (100 mL):

1. Primary Immunodeficiency Diseases (PID)

   • Globucel is commonly used to treat primary immunodeficiency disorders, where the body’s immune system is weakened or not functioning properly. These include conditions like X-linked agammaglobulinemia, common variable immunodeficiency (CVID), and severe combined immunodeficiency (SCID). In these conditions, the body lacks adequate immunoglobulins, and the injection provides the necessary antibodies to fight infections.

2. Secondary Immunodeficiency (e.g., HIV/AIDS)

   • It can be used in secondary immunodeficiency, where the immune system is weakened due to an underlying condition such as HIV/AIDS. It helps to boost the immune system by supplying antibodies that the body is unable to produce.

3. Autoimmune Disorders

   • Globucel is sometimes used in autoimmune conditions where the immune system attacks the body’s own tissues. Examples include:
     • Idiopathic thrombocytopenic purpura (ITP): A condition where platelets are destroyed by the immune system.
     • Guillain-Barré syndrome: A rare condition where the immune system attacks the nerves.
     • Myasthenia Gravis: An autoimmune neuromuscular disorder.

4. Post-Exposure Prophylaxis

   • It may be used to provide passive immunity following exposure to certain infections, such as hepatitis B or rabies, particularly in individuals who are at risk but not yet immune.

5. Organ Transplantation

   • After an organ transplant, immunoglobulin therapy like Globucel may be used to reduce the risk of infections and help with graft rejection.

6. Sepsis and Severe Infections

   • In some cases, immunoglobulin therapy is used to treat infections or as part of the treatment for sepsis, especially in individuals with weakened immune systems.

How Globucel Works:

Globucel provides immunoglobulins (antibodies) that are essential for fighting infections. It helps to boost the body's immune response by introducing antibodies that target pathogens like viruses and bacteria, improving the body’s ability to defend itself against infections.

Common Side Effects:

• Headache
• Fever
• Chills
• Fatigue
• Nausea
• Pain at the injection site
• Rash
• Elevated heart rate

Serious Side Effects:

• Kidney dysfunction
• Severe allergic reactions (anaphylaxis)
• Blood clot formation
• Hemolysis (destruction of red blood cells)
• Thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism)

Precautions:

• Kidney Health: People with pre-existing kidney disease should be closely monitored when receiving immunoglobulin therapy as there is a risk of kidney toxicity.
• Blood Pressure and Heart Health: Patients with cardiovascular issues should be monitored for any side effects related to blood pressure and heart rate.
• Pre-existing conditions: If you have history of allergic reactions or other serious conditions, inform your healthcare provider before administration.

Uses of Tolvasca Tablet

• Treatment of Low levels of sodium in the blood
• Syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Benefits of Tolvasca TabletIn Treatment of Low levels of sodium in the bloodLow levels of sodium may be caused due to multiple reasons such as excess of body fluids, heart disease, and kidney problems. There may be many symptoms such as nausea, headache confusion and the person may even need to get hospitalized. Tolvasca 15 Tablet helps to get rid of the excess fluids and retains sodium in the blood. This restores the normal sodium levels in our body and prevents further complications such as memory loss.